Stages of Sleep and Circadian Rhythms | MCAT Biology

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Sleep Stages
Deep Sleep
REM Sleep
Body Clock

Sleep Stages

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  • 1

    Sleep cycles through distinct brain wave patterns.

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    N1 is light sleep with theta waves and hypnic jerks.

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    N2 features spindles and K-complexes for staying asleep.

Basic neuroanatomy, particularly the structure and function of the hypothalamus and the endocrine system (including the pineal gland).
The fundamentals of electroencephalography (EEG) and how brain waves (alpha, beta, theta, delta) represent neural activity.
Concepts of physiological homeostasis and biological feedback loops.
The role of key neurotransmitters (such as serotonin, melatonin, GABA, and acetylcholine) in nervous system regulation.
Pathophysiology of sleep disorders, including insomnia, sleep apnea, narcolepsy, and somnambulism (sleepwalking).
The biochemical pathways of melatonin synthesis and the specific function of the suprachiasmatic nucleus (SCN) in response to light stimuli.
Theories of dreaming (such as the activation-synthesis hypothesis) and the role of REM and non-REM sleep in memory consolidation.
The pharmacological effects of stimulants, depressants, and sleep-aids on sleep architecture (such as how alcohol suppresses REM sleep).
780K views7.7Klikes7:56@khanacademymedicineOriginal Release: 2014-02-28

Sleep consists of four main stages (N1, N2, N3, and REM) that occur in approximately 90-minute cycles during a normal night, with N1 being light sleep featuring theta waves and hypnagogic hallucinations, N2 involving sleep spindles and K-complexes that help maintain sleep and consolidate memories, N3 (slow-wave sleep) producing delta waves and being the deepest stage where sleepwalking occurs, and REM sleep featuring rapid eye movements and muscle paralysis where most dreaming happens; these sleep cycles are regulated by circadian rhythms, which are the body's internal biological clocks that follow a 24-hour cycle and control body temperature, metabolism, and sleep-wake transitions, explaining why people feel sleepy at consistent times daily and why jet lag occurs when traveling across time zones.